Trends Microbiol. 2001 Jul;9(7):321-6.

Model systems: modeling human staphylococcal arthritis and sepsis in the mouse.

Tarkowski A, Collins LV, Gjertsson I, Hultgren OH, Jonsson IM, Sakiniene E, Verdrengh M.

Source

Dept of Rheumatology, University of Göteborg, Guldhedsgatan 10, S-413 46, Göteborg, Sweden. tarkow@mailer.mednet.gu.se

Abstract

The staphylococci have been recognized as serious pathogens for over a century and are the etiological agent of a variety of diseases ranging from mild cutaneous infections to often fatal forms of septic arthritis, endocarditis, toxic shock syndrome and sepsis. Despite intensive efforts to halt their spread, they remain the most common cause of community- and nosocomially acquired bacteremia. Murine models of Staphylocococus aureus-mediated arthritis and sepsis exist and are being used to gain a better understanding of the host-bacterium relationship as well to develop better methods of prevention and treatment.

PMID:: 11435106; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Libraries

LinkOut Holdings

Supplemental Content

Related citations

Staphylococcus aureus-induced inflammation and bone destruction in experimental models of septic arthritis. [J Periodontal Res. 1999]
Staphylococcus aureus-induced inflammation and bone destruction in experimental models of septic arthritis.
Josefsson E, Tarkowski A. J Periodontal Res. 1999 Oct; 34(7):387-92.
Are B lymphocytes of importance in severe Staphylococcus aureus infections? [Infect Immun. 2000]
Are B lymphocytes of importance in severe Staphylococcus aureus infections?
Gjertsson I, Hultgren OH, Stenson M, Holmdahl R, Tarkowski A. Infect Immun. 2000 May; 68(5):2431-4.
mgrA regulates staphylococcal virulence important for induction and progression of septic arthritis and sepsis. [Microbes Infect. 2008]
mgrA regulates staphylococcal virulence important for induction and progression of septic arthritis and sepsis.
Jonsson IM, Lindholm C, Luong TT, Lee CY, Tarkowski A. Microbes Infect. 2008 Oct; 10(12-13):1229-35. Epub 2008 Jul 23.
Review Rhabdomyolysis and aggravation of arthritis in a rheumatoid arthritis patient as a result of sepsis due to Staphylococcus aureus infection of a rheumatoid nodule; a catastrophic outcome. [Fukushima J Med Sci. 1999]
Review Rhabdomyolysis and aggravation of arthritis in a rheumatoid arthritis patient as a result of sepsis due to Staphylococcus aureus infection of a rheumatoid nodule; a catastrophic outcome.
Saito H, Miyata M, Ito M, Katakura K, Shishido H, Orikasa H, Munakata O, Saka M, Nishimaki T, Uchiyama T, et al. Fukushima J Med Sci. 1999 Dec; 45(2):125-33.
Review Staphylococcal superantigens: do they play a role in sepsis? [Arch Immunol Ther Exp (Warsz). 2005]
Review Staphylococcal superantigens: do they play a role in sepsis?
Holtfreter S, Bröker BM. Arch Immunol Ther Exp (Warsz). 2005 Jan-Feb; 53(1):13-27.

See reviews... See all...

Cited by 8 PubMed Central articles

Rhesus macaques (Macaca mulatta) are natural hosts of specific Staphylococcus aureus lineages. [PLoS One. 2011]
Rhesus macaques (Macaca mulatta) are natural hosts of specific Staphylococcus aureus lineages.
van den Berg S, van Wamel WJ, Snijders SV, Ouwerling B, de Vogel CP, Boelens HA, Willems RJ, Huijsdens XW, Verreck FA, Kondova I, et al. PLoS One. 2011; 6(10):e26170. Epub 2011 Oct 20.
Review Interaction of staphylococci with bone. [Int J Med Microbiol. 2010]
Review Interaction of staphylococci with bone.
Wright JA, Nair SP. Int J Med Microbiol. 2010 Feb; 300(2-3):193-204. Epub 2009 Nov 3.
Review Mapping the pathways to staphylococcal pathogenesis by comparative secretomics. [Microbiol Mol Biol Rev. 2006]
Review Mapping the pathways to staphylococcal pathogenesis by comparative secretomics.
Sibbald MJ, Ziebandt AK, Engelmann S, Hecker M, de Jong A, Harmsen HJ, Raangs GC, Stokroos I, Arends JP, Dubois JY, et al. Microbiol Mol Biol Rev. 2006 Sep; 70(3):755-88.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Model systems: modeling human staphylococcal arthritis and sepsis in the mouse.
Model systems: modeling human staphylococcal arthritis and sepsis in the mouse.
Trends Microbiol. 2001 Jul ;9(7):321-6.

PubMed
Global natural regulatory T cell depletion in active systemic lupus erythematosu...
Global natural regulatory T cell depletion in active systemic lupus erythematosus.
J Immunol. 2005 Dec 15 ;175(12):8392-400.

PubMed
OMERACT-OARSI initiative: Osteoarthritis Research Society International set of r...
OMERACT-OARSI initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited.
Osteoarthritis Cartilage. 2004 May ;12(5):389-99.

PubMed
Genetic epidemiology. Giant cell arteritis and polymyalgia rheumatica.
Genetic epidemiology. Giant cell arteritis and polymyalgia rheumatica.
Arthritis Res. 2001 ;3(3):154-7. Epub 2001 Feb 26 .

PubMed
Quality of life in arthritis patients using nonsteroidal anti-inflammatory drugs...
Quality of life in arthritis patients using nonsteroidal anti-inflammatory drugs.
Can J Gastroenterol. 1999 Mar ;13(2):129-33.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: