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    Curr Opin Genet Dev. 2000 Oct;10(5):529-35.

    Genetic control of cell size.

    Source

    Zoologisches Institut, Universität Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.

    Abstract

    Over the past 25 years, the genetic control of cell size has mainly been addressed in yeast, a single-celled organism. Recent insights from Drosophila have shed light on the signalling pathways responsible for adjusting and maintaining cell size in metazoans. Evidence is emerging for a signalling cascade conserved in evolution that links external nutrient sources to cell size.

    PMID:
    10980431
    [PubMed - indexed for MEDLINE]

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