Enzyme. 1975;19(1):15-23.

Beta-N-acetylhexosaminidase active on dermatan sulfate.

Abstract

The dodecasaccharide obtained by treating dermatan sulfate with testicular hyaluronidase, chondroitinase AC, and beta-glucuronidase was incubated with diluted, normal human serum at pH 4.5 or 7.0 followed by chondro-4-sulfatase at pH 7.0. Analyses of the reaction products indicate release of hexosamine but not further degradation of the substrate. It is concluded that normal human serum possesses an exo-beta-N-acetylhexosaminidase active on dermatan sulfate.

PMID:: 1093849; [PubMed - indexed for MEDLINE]

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Study on the degradation of glycosaminoglycans by canine liver lysosomal enzymes. II. The contributions of hyaluronidase, beta-glucuronidase, sulfatase, and beta-N-acetylhexosaminidase in the case of chondroitin 4-sulfate. [J Biochem. 1978]
Study on the degradation of glycosaminoglycans by canine liver lysosomal enzymes. II. The contributions of hyaluronidase, beta-glucuronidase, sulfatase, and beta-N-acetylhexosaminidase in the case of chondroitin 4-sulfate.
Hayashi S. J Biochem. 1978 Jan; 83(1):149-57.
Minimum substrate requirements of endoglycosidase activities toward dermatan sulfate by electrospray ionization-tandem mass spectrometry. [Glycobiology. 2008]
Minimum substrate requirements of endoglycosidase activities toward dermatan sulfate by electrospray ionization-tandem mass spectrometry.
Nielsen TC, Meikle PJ, Hopwood JJ, Fuller M. Glycobiology. 2008 Dec; 18(12):1119-28. Epub 2008 Sep 29.
Separation of dermatan sulfate from heparan sulfate in mucopolysaccharidosis urine by chromatography on Sephadex G-75. [Clin Chim Acta. 1976]
Separation of dermatan sulfate from heparan sulfate in mucopolysaccharidosis urine by chromatography on Sephadex G-75.
Herd JK, Forrest T, Tschida J. Clin Chim Acta. 1976 Apr 1; 68(1):1-9.
The copolymeric structure of pig skin dermatan sulphate. Isolation and characterization of L-idurono-sulphate-containing oligosaccharides from copolymeric chains. [Biochem J. 1974]
The copolymeric structure of pig skin dermatan sulphate. Isolation and characterization of L-idurono-sulphate-containing oligosaccharides from copolymeric chains.
Fransson LA, Cöster L, Havasmark B, Malmström A, Sjöberg I. Biochem J. 1974 Nov; 143(2):379-89.
Selective hydrolysis of chondroitin sulfates by hyaluronidase. [Biochemistry. 1984]
Selective hydrolysis of chondroitin sulfates by hyaluronidase.
Knudson W, Gundlach MW, Schmid TM, Conrad HE. Biochemistry. 1984 Jan 17; 23(2):368-75.

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