Biochim Biophys Acta. 1975 Apr 7;385(2):305-11.

Structure of the glycopeptide storage material in GM 1 gangliosidosis. Sequence determination with specific endo- and exoglycosidases.

Abstract

1. An endo-beta-galactosidase from Escherichia freundii, specific for the hydrolysis of desulfated keratan sulfate, quantitatively liberated a trisaccharide (Gal-GlcNAc-Gal) from a glycopeptide (Mr 1800) isolated from the liver of a patient with GM 1 (generalized) gangliosidosis. 2. The remaining glycopeptide was susceptible to sequential digestion with purified beta-N-acetylhexosaminidase and exo-beta-galactosidase from Jack Bean meal. 3. These and other studies established the structure of the stored glycopeptide to be:(see article) which probably represents the desulfated linkage region of skeletal keratan sulfate.

PMID:: 1092358; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Structure of the "keratosulfate-like" material in liver from a patient with G M1 -gangliosidosis ( -D-galactosidase deficiency). [Biochem Biophys Res Commun. 1973]
Structure of the "keratosulfate-like" material in liver from a patient with G M1 -gangliosidosis ( -D-galactosidase deficiency).
Tsay GC, Dawson G. Biochem Biophys Res Commun. 1973 Jun 8; 52(3):759-66.
Presence of glycoproteins containing the polylactosamine structure in brain and liver of GM1 gangliosidosis patients. Comparative study between clinical types I and II, using endo-beta-galactosidase enzyme. [Neurochem Pathol. 1986]
Presence of glycoproteins containing the polylactosamine structure in brain and liver of GM1 gangliosidosis patients. Comparative study between clinical types I and II, using endo-beta-galactosidase enzyme.
Berra B, De Gasperi R, Rapelli S, Okada S, Li SC, Li YT. Neurochem Pathol. 1986 Apr; 4(2):107-17.
Studies on the carbohydrate-protein linkage region in bovine corneal keratan sulfate. II. Structural studies on linkage region-enriched neutral glycopeptides. [J Biochem. 1983]
Studies on the carbohydrate-protein linkage region in bovine corneal keratan sulfate. II. Structural studies on linkage region-enriched neutral glycopeptides.
Yamaguchi H. J Biochem. 1983 Jul; 94(1):215-21.
Fractionation and characterization of glycopeptides and oligosaccharides from the liver of a patient with G-M1-gangliosidosis of type I. [Ital J Biochem. 1974]
Fractionation and characterization of glycopeptides and oligosaccharides from the liver of a patient with G-M1-gangliosidosis of type I.
Calatroni A. Ital J Biochem. 1974 Sep-Oct; 23(5):329-44.
Review Glycosphingolipids: structure, biological source, and properties. [Methods Enzymol. 1978]
Review Glycosphingolipids: structure, biological source, and properties.
Macher BA, Sweeley CC. Methods Enzymol. 1978; 50:236-51.

See reviews... See all...

Cited by 1 PubMed Central article

The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu. [Retrovirology. 2009]
The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu.
Andrew AJ, Miyagi E, Kao S, Strebel K. Retrovirology. 2009 Sep 8; 6:80. Epub 2009 Sep 8.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Structure of the glycopeptide storage material in GM 1 gangliosidosis. Sequence ...
Structure of the glycopeptide storage material in GM 1 gangliosidosis. Sequence determination with specific endo- and exoglycosidases.
Biochim Biophys Acta. 1975 Apr 7 ;385(2):305-11.

PubMed
Innate immunity.
Innate immunity.
N Engl J Med. 2000 Aug 3 ;343(5):338-44.

PubMed
A novel murine oncornavirus with dual eco- and xenotropic properties.
A novel murine oncornavirus with dual eco- and xenotropic properties.
Proc Natl Acad Sci U S A. 1975 Dec ;72(12):5150-5.

PubMed
Leukaemia disease genes: large-scale cloning and pathway predictions.
Leukaemia disease genes: large-scale cloning and pathway predictions.
Nat Genet. 1999 Nov ;23(3):348-53.

PubMed
Murine leukemia virus: detection of unintegrated double-stranded DNA forms of th...
Murine leukemia virus: detection of unintegrated double-stranded DNA forms of the provirus.
Proc Natl Acad Sci U S A. 1975 Feb ;72(2):447-51.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Structure of the glycopeptide storage material in GM 1 gangliosidosis. Sequence determination with specific endo- and exoglycosidases.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 1 PubMed Central article

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information