Curr Biol. 2000 Apr 20;10(8):R318-20.

Towards a circuit engineering discipline.

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Department of Developmental Biology, School of Medicine, Stanford University, Stanford 94305, USA. mcadams@cmgm.stanford.edu

Abstract

Genetic circuits can now be engineered that perform moderately complicated switching functions or exhibit predictable dynamical behavior. These 'forward engineering' techniques may have to be combined with directed evolution techniques to produce robustness comparable with naturally occurring circuits.

PMID:: 10801411; [PubMed - indexed for MEDLINE]

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