Clin Sci Mol Med Suppl. 1976 Dec;3:697s-698s.

Thrombolysis by ultrasound.

Trübestein G, Engel C, Etzel F, Sobbe A, Cremer H, Stumpff U.

Abstract

1. A new method of destroying thrombi in blood vessels by ultrasound and simultaneously removing them is reported. 2. Experiments were performed in twenty dogs with artificial thrombi in the iliac and femoral arteries and veins. The length of the thrombi ranged from 4 to 5 cm and the age from 12 h to 10 days. The unit used consisted of a generator, a frequency counter, an ultrasonic transducer with the hollow waveguide and a vacuum pump. For protection of the vessel wall the guide is surrounded by a plastic tube. The ultrasonic frequency is 26-5 kHz, the amplitude 25-30 micronm. The time needed to destroy the thrombus by ultrasound and suck out the thrombotic material ranged from 2-5 to 5 min. 3. To check side effects, experiments were performed in forty-four dogs. No significant changes were seen in the fibrinolytic system or microscopic structure of the vessel wall after ultrasound.

PMID:: 1071713; [PubMed - indexed for MEDLINE]

MeSH Terms

LinkOut - more resources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

[Removal of intravascular thrombi by means of ultrasonics. Experimental study with a new method and its clinical use]. [Fortschr Med. 1978]
[Removal of intravascular thrombi by means of ultrasonics. Experimental study with a new method and its clinical use].
Trübestein G. Fortschr Med. 1978 Apr 13; 96(14):755-60.
[Embolism by ultrasound-thrombolysis (author's transl)]. [Langenbecks Arch Chir. 1976]
[Embolism by ultrasound-thrombolysis (author's transl)].
Trübestein G, Engel C, Stumpff U, Wuttke H, Sobbe A. Langenbecks Arch Chir. 1976 Feb 10; 340(3):199-205.
[Intravascular ultrasound thrombolysis for recanalization of peripheral arteries: evaluation of an in vitro model and results of a pilot-study]. [Rofo. 2002]
[Intravascular ultrasound thrombolysis for recanalization of peripheral arteries: evaluation of an in vitro model and results of a pilot-study].
Krüger K, Deissler P, Zähringer M, Coburger S, Gawenda M, Lackner K. Rofo. 2002 Oct; 174(10):1261-8.
Review Ultrasound and thrombolysis. [Vasc Med. 2001]
Review Ultrasound and thrombolysis.
Francis CW, Suchkova VN. Vasc Med. 2001; 6(3):181-7.
Review Noninvasive transcutaneous low frequency ultrasound enhances thrombolysis in peripheral and coronary arteries. [Echocardiography. 2001]
Review Noninvasive transcutaneous low frequency ultrasound enhances thrombolysis in peripheral and coronary arteries.
Siegel RJ, Atar S, Fishbein MC, Brasch AV, Peterson TM, Nagai T, Pal D, Nishioka T, Chae JS, Birnbaum Y, et al. Echocardiography. 2001 Apr; 18(3):247-57.

See reviews... See all...

Cited by 4 PubMed Central articles

Noninvasive treatment of deep venous thrombosis using pulsed ultrasound cavitation therapy (histotripsy) in a porcine model. [J Vasc Interv Radiol. 2011]
Noninvasive treatment of deep venous thrombosis using pulsed ultrasound cavitation therapy (histotripsy) in a porcine model.
Maxwell AD, Owens G, Gurm HS, Ives K, Myers DD Jr, Xu Z. J Vasc Interv Radiol. 2011 Mar; 22(3):369-77. Epub 2010 Dec 30.
Review Microbubbles in ultrasound-triggered drug and gene delivery. [Adv Drug Deliv Rev. 2008]
Review Microbubbles in ultrasound-triggered drug and gene delivery.
Hernot S, Klibanov AL. Adv Drug Deliv Rev. 2008 Jun 30; 60(10):1153-66. Epub 2008 Apr 3.
Can pulsed ultrasound increase tissue damage during ischemia? A study of the effects of ultrasound on infarcted and non-infarcted myocardium in anesthetized pigs. [BMC Cardiovasc Disord. 2005]
Can pulsed ultrasound increase tissue damage during ischemia? A study of the effects of ultrasound on infarcted and non-infarcted myocardium in anesthetized pigs.
Olivecrona GK, Härdig BM, Roijer A, Block M, Grins E, Persson HW, Johansson L, Olsson B. BMC Cardiovasc Disord. 2005 Apr 15; 5(1):8. Epub 2005 Apr 15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Thrombolysis by ultrasound.
Thrombolysis by ultrasound.
Clin Sci Mol Med Suppl. 1976 Dec ;3:697s-698s.

PubMed
Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in ...
Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene.
N Engl J Med. 2000 Mar 16 ;342(11):770-80.

PubMed
Vitamin A-containing lipocytes and formation of type III collagen in liver injur...
Vitamin A-containing lipocytes and formation of type III collagen in liver injury.
Proc Natl Acad Sci U S A. 1976 Oct ;73(10):3719-22.

PubMed
tRNA 3' processing in plants: nuclear and mitochondrial activities differ.
tRNA 3' processing in plants: nuclear and mitochondrial activities differ.
Biochemistry. 2000 Feb 29 ;39(8):2096-105.

PubMed
Scrotal tongue and geographic tongue: polygenic and associated traits.
Scrotal tongue and geographic tongue: polygenic and associated traits.
Oral Surg Oral Med Oral Pathol. 1976 Nov ;42(5):591-6.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Thrombolysis by ultrasound.

Abstract

MeSH Terms

MeSH Terms

LinkOut - more resources

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 4 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information