Science. 2000 Feb 4;287(5454):845-8.

Cross-species interactions between malaria parasites in humans.

Bruce MC, Donnelly CA, Alpers MP, Galinski MR, Barnwell JW, Walliker D, Day KP.

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Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, UK. marian.bruce@ceid.ox.ac.uk

Abstract

The dynamics of multiple Plasmodium infections in asymptomatic children living under intense malaria transmission pressure provide evidence for a density-dependent regulation that transcends species as well as genotype. This regulation, in combination with species- and genotype-specific immune responses, results in nonindependent, sequential episodes of infection with each species.

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Cross-species interactions between malaria parasites in humans.

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