Proc Natl Acad Sci U S A. 1975 Feb;72(2):447-51.

Murine leukemia virus: detection of unintegrated double-stranded DNA forms of the provirus.

Abstract

Infection of JLS V-9 (mouse bone marrow) cells with Moloney murine leukemia virus leads to appearance of virus-specific DNA in the low molecular weight DNA fraction from infected cells. Most of this DNA is double-stranded. Two discrete forms of double-stranded DNA, both of molecular weight 6 times 10-6, have been characterized. One of these forms is closed-circular, supercoiled DNA; the other form is a mixture of nicked-circular and linear DNA.

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PMCID:: PMC432328

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