Arch Dis Child. 1999 Feb;80(2):188-91.

Joint hypermobility and genetic collagen disorders: are they related?

Source

Hypermobility Clinic, UCL Hospitals, London, UK.

Abstract

The HDCTs constitute a heterogeneous group of rare genetically determined diseases, the best known of which are Ehlers-Danlos and Marfan syndromes and osteogenesis imperfecta. Hypermobility is a feature common to them all, but it is also a feature that is highly prevalent in the population at large. Symptomatic hypermobile subjects (whose symptoms are attributable to their hypermobility) are said to be suffering from the benign joint hypermobility syndrome, which has many features that overlap with the HDCTs. It is not yet known whether there is a variety of hypermobility (symptomatic or otherwise) that is not part of a connective tissue disorder.

PMID:: 10325741; [PubMed - indexed for MEDLINE]
PMCID: PMC1717821

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Collagen

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Libraries

LinkOut Holdings

Supplemental Content

Related citations

Review Heritable disorders of connective tissue. [Baillieres Best Pract Res Clin Rheumatol. 2...]
Review Heritable disorders of connective tissue.
Grahame R. Baillieres Best Pract Res Clin Rheumatol. 2000 Jun; 14(2):345-61.
Joint mobility with particular reference to racial variation and inherited connective tissue disorders. [Br J Rheumatol. 1987]
Joint mobility with particular reference to racial variation and inherited connective tissue disorders.
Wordsworth P, Ogilvie D, Smith R, Sykes B. Br J Rheumatol. 1987 Feb; 26(1):9-12.
Review The genetic basis of the joint hypermobility syndromes. [Rheumatology (Oxford). 2006]
Review The genetic basis of the joint hypermobility syndromes.
Malfait F, Hakim AJ, De Paepe A, Grahame R. Rheumatology (Oxford). 2006 May; 45(5):502-7. Epub 2006 Jan 17.
Review Joint hypermobility syndromes. [Curr Opin Rheumatol. 1996]
Review Joint hypermobility syndromes.
Raff ML, Byers PH. Curr Opin Rheumatol. 1996 Sep; 8(5):459-66.
Molecular mechanisms of disease in inherited disorders of collagen metabolism. [Prog Clin Biol Res. 1982]
Molecular mechanisms of disease in inherited disorders of collagen metabolism.
Byers PH, Barsh GS, Holbrook KA. Prog Clin Biol Res. 1982; 103 Pt B:211-22.

See reviews... See all...

Cited by 9 PubMed Central articles

Comparative clinical profile of postural orthostatic tachycardia patients with and without joint hypermobility syndrome. [Indian Pacing Electrophysiol J. 2010]
Comparative clinical profile of postural orthostatic tachycardia patients with and without joint hypermobility syndrome.
Kanjwal K, Saeed B, Karabin B, Kanjwal Y, Grubb BP. Indian Pacing Electrophysiol J. 2010 Apr 1; 10(4):173-8. Epub 2010 Apr 1.
Prevalence of joint hypermobility and patterns of articular manifestations in patients with inflammatory bowel disease. [Gastroenterol Res Pract. 2009]
Prevalence of joint hypermobility and patterns of articular manifestations in patients with inflammatory bowel disease.
Vounotrypidis P, Efremidou E, Zezos P, Pitiakoudis M, Maltezos E, Lyratzopoulos N, Kouklakis G. Gastroenterol Res Pract. 2009; 2009:924138. Epub 2010 Feb 11.
Neonatal familial Evans syndrome associated with joint hypermobility and mitral valve regurgitation in three siblings in a Saudi Arab family. [Ann Saudi Med. 2009]
Neonatal familial Evans syndrome associated with joint hypermobility and mitral valve regurgitation in three siblings in a Saudi Arab family.
Ahmed FE, Albakrah MS. Ann Saudi Med. 2009 May-Jun; 29(3):227-30.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Joint hypermobility and genetic collagen disorders: are they related?
Joint hypermobility and genetic collagen disorders: are they related?
Arch Dis Child. 1999 Feb ;80(2):188-91.

PubMed
The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobi...
The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS).
J Rheumatol. 2000 Jul ;27(7):1777-9.

PubMed
Summary of worldwide pediatric malignancies reported after exposure to etanercep...
Summary of worldwide pediatric malignancies reported after exposure to etanercept.
Pediatr Rheumatol Online J. 2010 Jun 14 ;8:18.

PubMed
Incidence of temporomandibular involvement in juvenile idiopathic arthritis.
Incidence of temporomandibular involvement in juvenile idiopathic arthritis.
Scand J Rheumatol. 2007 May-Jun ;36(3):184-8.

PubMed
A prospective study of magnetic resonance and radiographic imaging in relation t...
A prospective study of magnetic resonance and radiographic imaging in relation to symptoms and clinical findings of the temporomandibular joint in children with juvenile idiopathic arthritis.
J Rheumatol. 2008 Aug ;35(8):1668-75. Epub 2008 Jul 15 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: