Arabidopsis ent-kaurene oxidase catalyzes three st...[Plant Physiol. 1999]

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1: Plant Physiol. 1999 Feb;119(2):507-10. Links

Arabidopsis ent-kaurene oxidase catalyzes three steps of gibberellin biosynthesis.

Helliwell CA, Poole A, Peacock WJ, Dennis ES.

Commonwealth Scientific and Industrial Research Organization, Plant Industry, G.P.O. Box 1600, Canberra, ACT 2601, Australia. chrish@pican.pi.csiro.au

The Arabidopsis GA3 cDNA was expressed in yeast (Saccharomyces cerevisiae) and the ability of the transformed yeast cells to metabolize ent-kaurene was tested. We show by full-scan gas chromatography-mass spectrometry that the transformed cells produce ent-kaurenoic acid, and demonstrate that the single enzyme GA3 (ent-kaurene oxidase) catalyzes the three steps of gibberellin biosynthesis from ent-kaurene to ent-kaurenoic acid.

PMID: 9952446 [PubMed - indexed for MEDLINE]

PMCID: PMC32127

The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.
Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):2065-70. Epub 2001 Feb 6.

[Proc Natl Acad Sci U S A. 2001]
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The P450-4 gene of Gibberella fujikuroi encodes ent-kaurene oxidase in the gibberellin biosynthesis pathway.
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[Appl Environ Microbiol. 2001]
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Plant Physiol. 1999 Feb; 119(2):365-70.

[Plant Physiol. 1999]
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