The HIS4 gene from the yeast Kluyveromyces lactis. [Yeast. 1998]

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1: Yeast. 1998 May;14(7):687-91. Links

The HIS4 gene from the yeast Kluyveromyces lactis.

Freire-Picos MA, Hampsey M, Cerdán ME.

Departamento de Biologia Celular y Molecular, Facultad de Ciencias, Universidad de La Coruña, Spain.

The Kluyveromyces lactis HIS4 gene was cloned by complementation of a Saccharomyces cerevisiae his4 mutant. Sequence analysis revealed a 2388 bp open reading frame encoding a single polypeptide predicted to encompass three distinct enzymatic activities (phosphoribosyl-AMP cyclohydrolase, phosphoribosyl-ATP pyrophosphohydrolase and histidinol dehydrogenase). This structural organization is strikingly similar to that of the His4 proteins from S. cerevisiae and Pichia pastoris. Transcript analysis detected a single mRNA species of 2.5 kb.

PMID: 9639316 [PubMed - indexed for MEDLINE]

Cloning and sequence of a 3.835 kbp DNA fragment containing the HIS4 gene and a fragment of a PEX5-like gene from Candida albicans.
Yeast. 1998 Sep 15; 14(12):1147-57.

[Yeast. 1998]
Kluyveromyces lactis HIS4 transcriptional regulation: similarities and differences to Saccharomyces cerevisiae HIS4 gene.
FEBS Lett. 1999 Sep 10; 458(1):72-6.

[FEBS Lett. 1999]
The Pichia pastoris HIS4 gene: nucleotide sequence, creation of a non-reverting his4 deletion mutant, and development of HIS4-based replicating and integrating plasmids.
Curr Genet. 1994 Nov-Dec; 26(5-6):443-50.

[Curr Genet. 1994]
ReviewThe Kluyveromyces lactis repertoire of transcriptional regulators.
FEMS Yeast Res. 2006 May; 6(3):325-35.

[FEMS Yeast Res. 2006]
ReviewApplication of yeasts in gene expression studies: a comparison of Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis -- a review.
Gene. 1997 Apr 29; 190(1):87-97.

[Gene. 1997]
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