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1: Infect Immun. 1998 Jun;66(6):2984-6.Click here to read Click here to read Links

Extracellular release of antigenic proteins by Helicobacter pylori.

Cao P, McClain MS, Forsyth MH, Cover TL.

Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2605, USA.

Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). H. pylori antigens may be released into the extracellular space by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle formation.

PMID: 9596777 [PubMed - indexed for MEDLINE]

PMCID: PMC108299