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1: Yeast. 1995 Sep 30;11(12):1171-7.Links

Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe.

Coblenz A, Wolf K.

Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule Aachen, Germany.

By complementation of a mutant resistant to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) we have identified the gcs1 gene, encoding a putative gamma-glutamylcysteine synthetase. The gene is possibly interrupted by two introns and has 49% identical and 80% similar amino acids compared with the homologous protein from rat. In comparison with the Saccharomyces cerevisiae homologue it possesses 41% identical and 74% similar amino acids.

PMID: 8619315 [PubMed - indexed for MEDLINE]