Sequence of the Candida albicans erg7 gene.
Department of Chemistry, Texas A & M University, College Station 77843-3255.
The nucleotide sequence of the Candida albicans erg7 gene, which complements erg7 mutants of Saccharomyces cerevisiae and restores oxidosqualene cyclase activity, was determined. The gene encodes a 728-aa protein that displays homology with squalene-hopene cyclase, providing further evidence that erg7 is the gene encoding 2,3-oxidosqualene cyclase.
PMID: 8486282 [PubMed - indexed for MEDLINE]