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Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.
Department of Pharmacology, Nagoya University School of Medicine, Japan.
We purified and sequenced from bovine brain a novel calcium-binding protein. This protein which we named neurocalcin has 3 putative EF hand motifs and a close homology with recoverin which activates guanylate cyclase Ca2+ dependently. Neurocalcin has at least 6 isoforms and is expressed in the central nervous system (CNS), retina and adrenal gland. Considering unique distribution of neurocalcin, this protein may an important physiological role which differs from that of visinin or recoverin.
PMID: 8387172 [PubMed - indexed for MEDLINE]
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Cited by 5 PubMed Central articles
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Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality.
Ikura M, Ames JB.
Proc Natl Acad Sci U S A. 2006 Jan 31; 103(5):1159-64. Epub 2006 Jan 23.
[Proc Natl Acad Sci U S A. 2006]
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Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies.
Sokal I, Li N, Klug CS, Filipek S, Hubbell WL, Baehr W, Palczewski K.
J Biol Chem. 2001 Nov 16; 276(46):43361-73. Epub 2001 Aug 27.
[J Biol Chem. 2001]
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Unc-1: a stomatin homologue controls sensitivity to volatile anesthetics in Caenorhabditis elegans.
Rajaram S, Sedensky MM, Morgan PG.
Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15):8761-6.
[Proc Natl Acad Sci U S A. 1998]
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