The mannitol repressor (MtlR) of Escherichia coli. [J Bacteriol. 1994]

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1: J Bacteriol. 1994 Feb;176(3):840-7. Links

The mannitol repressor (MtlR) of Escherichia coli.

Figge RM, Ramseier TM, Saier MH Jr.

Department of Biology, University of California at San Diego, La Jolla 92093-0116.

The mannitol operon of Escherichia coli, encoding the mannitol-specific enzyme II of the phosphotransferase system (Mt1A) and mannitol phosphate dehydrogenase (Mt1D), is here shown to contain a single additional downstream open reading frame which encodes the mannitol repressor (Mt1R). Mt1R contains 195 amino acids and has a calculated molecular weight of 21,990 and a calculated pI of 4.5. It is homologous to the product of an open reading frame (URF2D) upstream of the E. coli gapB gene but represents a novel type of transcriptional regulatory protein.

PMID: 8300537 [PubMed - indexed for MEDLINE]

PMCID: PMC205122

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