Nucleotide sequence of the Escherichia coli K12 hi...[J Mol Biol. 1994]

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1: J Mol Biol. 1994 Jun 10;239(3):433-5. Links

Nucleotide sequence of the Escherichia coli K12 histidine operon revisited.

Jovanović G, Kostić T, Janković M, Savić DJ.

Institute of Molecular Genetics and Genetic Engineering, Belgrade, Yugoslavia.

We report on a significant difference between the published nucleotide sequence of the Escherichia coli K12 histidine operon and our sequencing results repeatedly obtained from a number of different E. coli K12 strains. The discrepancies include 39 base-pair changes and one addition located predominantly in the proximal portion of the operon. Our data also suggest that neutral and near-neutral mutations do not accumulate to a significant extent in the histidine operon of E. coli strains harbouring strong mutator alleles.

PMID: 8201624 [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

Gene replacement with linear DNA fragments in wild-type Escherichia coli: enhancement by Chi sites.
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Cited by 2 PubMed Central articles

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