Molecular cloning of rat RAC protein kinase alpha ...[Biochem Biophys Res Commun. 1994]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Biochem Biophys Res Commun. 1994 Nov 30;205(1):817-25. Links

Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta.

Konishi H, Shinomura T, Kuroda S, Ono Y, Kikkawa U.

Biosignal Research Center, Faculty of Science Kobe University, Japan.

cDNAs of RAC protein kinases (RAC-PK) alpha and beta were cloned from a rat testis cDNA library. The predicted open reading frames encode 480 and 481 amino acids of RAC-PK alpha and beta, respectively, and the rat RAC-PK alpha and beta have sequences conserved among different mammalian species such as the pleckstrin homology domain at their amino-terminal region and the protein-serine/threonine kinase catalytic domain at their carboxyl-terminal region. RNA blot analysis showed wide distribution of two RAC-PK in rat tissues. Immunoprecipitation analysis revealed that RAC-PK alpha and beta associate with protein kinase C zeta through the pleckstrin homology domain in vitro, suggesting the interaction between RAC-PK and protein kinase C.

PMID: 7999118 [PubMed - indexed for MEDLINE]

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins.
Biochem Biophys Res Commun. 1995 Nov 13; 216(2):526-34.

[Biochem Biophys Res Commun. 1995]
Molecular cloning of a second form of rac protein kinase.
Cell Regul. 1991 Dec; 2(12):1001-9.

[Cell Regul. 1991]
Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase.
EMBO J. 1995 Sep 1; 14(17):4288-95.

[EMBO J. 1995]
Review[Heterogeneity of protein kinase C]
Postepy Biochem. 1989; 35(3):245-52.

[Postepy Biochem. 1989]
Review[Study of the heterogeneity and structures of protein kinase C]
Seikagaku. 1989 Jul; 61(7):551-68.

[Seikagaku. 1989]
» See reviews... | » See all...

Cited by 11 PubMed Central articles

Late Simian virus 40 transcription factor is a target of the phosphoinositide 3-kinase/Akt pathway in anti-apoptotic Alzheimer's amyloid precursor protein signalling.
Kashour T, Burton T, Dibrov A, Amara FM. Biochem J. 2003 Mar 15; 370(Pt 3):1063-75.

[Biochem J. 2003]
Akt-dependent cytokine production in mast cells.
Kitaura J, Asai K, Maeda-Yamamoto M, Kawakami Y, Kikkawa U, Kawakami T. J Exp Med. 2000 Sep 4; 192(5):729-40.

[J Exp Med. 2000]
Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B.
Takaishi H, Konishi H, Matsuzaki H, Ono Y, Shirai Y, Saito N, Kitamura T, Ogawa W, Kasuga M, Kikkawa U, et al. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):11836-41.

[Proc Natl Acad Sci U S A. 1999]
» See all...

Recent Activity

Clear Turn Off Turn On

Molecular cloning of rat RAC protein kinase alpha and beta and their association with prot...Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta.

Related articles

Cited by 11 PubMed Central articles

Recent Activity