The complete cDNA derived sequence of the rat prol...[Gene. 1994]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Gene. 1994 Nov 18;149(2):391-2.Links

The complete cDNA derived sequence of the rat prolyl 4-hydroxylase alpha subunit.

Hopkinson I, Smith SA, Donne A, Gregory H, Franklin TJ, Grant ME, Rosamond J.

School of Biological Sciences, University of Manchester, UK.

A rat cDNA encoding the prolyl 4-hydroxylase alpha subunit (P4H alpha) was isolated and sequenced. The primary aa sequence deduced from the nucleotide sequence reveals a 534-aa protein that shows extensive aa identity with the human (88%) and chick (77%) P4H alpha.

PMID: 7959029 [PubMed - indexed for MEDLINE]

Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.
Proc Natl Acad Sci U S A. 1989 Jun; 86(12):4392-6.

[Proc Natl Acad Sci U S A. 1989]
Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.
Proc Natl Acad Sci U S A. 1995 May 9; 92(10):4427-31.

[Proc Natl Acad Sci U S A. 1995]
Cloning, baculovirus expression, and characterization of the alpha subunit of prolyl 4-hydroxylase from the nematode Caenorhabditis elegans. This alpha subunit forms an active alpha beta dimer with the human protein disulfide isomerase/beta subunit.
J Biol Chem. 1994 Oct 28; 269(43):26746-53.

[J Biol Chem. 1994]
ReviewCollagen hydroxylases and the protein disulfide isomerase subunit of prolyl 4-hydroxylases.
Adv Enzymol Relat Areas Mol Biol. 1998; 72:325-98.

[Adv Enzymol Relat Areas Mol Biol. 1998]
ReviewActivation of prolyl hydroxylase by ascorbic acid.
Nutr Rev. 1973 Aug; 31(8):255-7.

[Nutr Rev. 1973]
» See reviews... | » See all...

Cited by 2 PubMed Central articles

Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans.
Friedman L, Higgin JJ, Moulder G, Barstead R, Raines RT, Kimble J. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4736-41.

[Proc Natl Acad Sci U S A. 2000]
Co-expression of the alpha subunit of human prolyl 4-hydroxylase with BiP polypeptide in insect cells leads to the formation of soluble and insoluble complexes. Soluble alpha-subunit-BiP complexes have no prolyl 4-hydroxylase activity.
Veijola J, Pihlajaniemi T, Kivirikko KI. Biochem J. 1996 Apr 15; 315 ( Pt 2):613-8.

[Biochem J. 1996]

Recent Activity

Clear Turn Off Turn On

The complete cDNA derived sequence of the rat prolyl 4-hydroxylase alpha subunit.The complete cDNA derived sequence of the rat prolyl 4-hydroxylase alpha subunit.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

The complete cDNA derived sequence of the rat prolyl 4-hydroxylase alpha subunit.

Related articles

Cited by 2 PubMed Central articles

Recent Activity