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Molecular cloning of rat bone morphogenetic protein (BMP) type IA receptor and its expression during ectopic bone formation induced by BMP.
Department of Biochemistry, Tokyo Medical and Dental University, Japan.
A cDNA for the rat bone morphogenetic protein (BMP) type IA receptor (BMPR-IA) was isolated from a dental pulp cell cDNA library. The rat BMPR-IA cDNA encodes a protein of 532 amino acids with a single transmembrane domain and a putative serine/threonine kinase domain. The overall amino acid sequence identity between the rat and human BMPR-IA was 97%. Reverse transcriptase-polymerase chain reaction analysis revealed that BMPR-IA mRNA was highly expressed in the BMP-induced bone forming tissues throughout the stages tested.
PMID: 7945360 [PubMed - indexed for MEDLINE]
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Cited by 4 PubMed Central articles
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Short-term effects of amelogenin gene splice products A+4 and A-4 implanted in the exposed rat molar pulp.
Jegat N, Septier D, Veis A, Poliard A, Goldberg M.
Head Face Med. 2007 Dec 21; 3:40. Epub 2007 Dec 21.
[Head Face Med. 2007]
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The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle.
Erickson GF, Shimasaki S.
Reprod Biol Endocrinol. 2003 Feb 5; 1:9. Epub 2003 Feb 5.
[Reprod Biol Endocrinol. 2003]
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A functional bone morphogenetic protein system in the ovary.
Shimasaki S, Zachow RJ, Li D, Kim H, Iemura S, Ueno N, Sampath K, Chang RJ, Erickson GF.
Proc Natl Acad Sci U S A. 1999 Jun 22; 96(13):7282-7.
[Proc Natl Acad Sci U S A. 1999]
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