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1: Gene. 1995 Mar 21;155(1):139-40.Click here to read Links

Cloning and sequence analysis of an ERG24 homolog from Schizosaccharomyces pombe.

Smith S.

Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021, USA.

The Schizosaccharomyces pombe (Sp) erg24 cDNA, encoding C-14 sterol reductase (erg24p), has been cloned and sequenced. The nucleotide sequence of Sp erg24 contains an open reading frame encoding a 424-amino-acid protein. The deduced aa sequence of Sp erg24 shows significant homology with Saccharomyces cerevisiae (Sc) Erg24p, as well as with other members of a larger gene family that includes yeast C-24(28) sterol reductase (Erg4p) and a vertebrate inner nuclear membrane protein, the lamin B receptor (LBR).

PMID: 7698661 [PubMed - indexed for MEDLINE]