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Sequence of the Rhodococcus equi gene encoding the virulence-associated 15-17-kDa antigens.
National Institute of Animal Health, Ibaraki, Japan.
The nucleotide sequence of the Rhodococcus equi gene encoding the virulence-associated 15-17-kDa antigens, located on plasmid pREAT701, has been determined. The gene encodes a 19-kDa protein of 189 amino acids, with an Ala-rich leader signal sequence (SS). At least five SS peptidase cleavage sites were found in this region. The molecular diversity of 15-17-kDa antigens might be attributed to the multiple SS peptidase cleavage sites.
PMID: 7698659 [PubMed - indexed for MEDLINE]
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Cited by 11 PubMed Central articles
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Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids.
Letek M, Ocampo-Sosa AA, Sanders M, Fogarty U, Buckley T, Leadon DP, González P, Scortti M, Meijer WG, Parkhill J, et al.
J Bacteriol. 2008 Sep; 190(17):5797-805. Epub 2008 Jul 7.
[J Bacteriol. 2008]
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Characterization of virulence plasmids and serotyping of rhodococcus equi isolates from submaxillary lymph nodes of pigs in Hungary.
Makrai L, Takayama S, Dénes B, Hajtós I, Sasaki Y, Kakuda T, Tsubaki S, Major A, Fodor L, Varga J, et al.
J Clin Microbiol. 2005 Mar; 43(3):1246-50.
[J Clin Microbiol. 2005]
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B-Cell epitope mapping of the VapA protein of Rhodococcus equi: implications for early detection of R. equi disease in foals.
Vanniasinkam T, Barton MD, Heuzenroeder MW.
J Clin Microbiol. 2001 Apr; 39(4):1633-7.
[J Clin Microbiol. 2001]
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