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YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.
Department of Medicine I, University of Freiburg, Germany.
The characterization of three YAC/P1 contigs from adjacent segments of the central region of mouse Chromosome (Chr) 11 is described. These contigs are based upon 63 YACs and 40 P1 recombinants. From these clones, 185 end sequences were obtained, of which 147 sequences could be converted into sequence-tagged sites and mapped within the three contigs. Deletions were detected in 16 out of 63 YACs; 19 of 63 YACs were found to be chimeric. No such aberrations were found in P1 recombinants. A total of 22 public and 34 newly developed microsatellite markers were unambiguously localized to and ordered in the contigs. In the cryb1/Nf1 interval of the central contig, several new genes have been identified by exon trapping and precisely localized with respect to known STS markers.
PMID: 7626882 [PubMed - indexed for MEDLINE]
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Cited by 6 PubMed Central articles
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Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein.
Mack GJ, Compton DA.
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[Proc Natl Acad Sci U S A. 2001]
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Campomelic dysplasia translocation breakpoints are scattered over 1 Mb proximal to SOX9: evidence for an extended control region.
Pfeifer D, Kist R, Dewar K, Devon K, Lander ES, Birren B, Korniszewski L, Back E, Scherer G.
Am J Hum Genet. 1999 Jul; 65(1):111-24.
[Am J Hum Genet. 1999]
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Quantitative trait loci affecting body weight and fatness from a mouse line selected for extreme high growth.
Brockmann GA, Haley CS, Renne U, Knott SA, Schwerin M.
Genetics. 1998 Sep; 150(1):369-81.
[Genetics. 1998]
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