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The capsid protein of Semliki Forest virus has clusters of basic amino acids and prolines in its amino-terminal region.
The amino acid sequence of the capsid (C) protein was deduced from the nucleotide sequence of the C gene. This part of the viral 42S RNA genome was transcribed into double-stranded cDNA. The cDNA was cloned in the Escherichia coli chi 1776-pBR322 host-vector system and then the base sequence was determined with the technique described by Maxam and Gilbert. The amino acid sequence of the C protein shows a clustering of basic amino acids and prolines within the first 110 amino acids.
PMID: 6935652 [PubMed - indexed for MEDLINE]
PMCID: PMC350287
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Cited by 47 PubMed Central articles
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