-
Molecular cloning of a cDNA encoding human antihaemophilic factor.
Toole JJ,
Knopf JL,
Wozney JM,
Sultzman LA,
Buecker JL,
Pittman DD,
Kaufman RJ,
Brown E,
Shoemaker C,
Orr EC, et al.
A complete copy of the mRNA sequences encoding human coagulation factor VIII:C has been cloned and expressed. The DNA sequence predicts a single chain precursor of 2,351 amino acids with a relative molecular mass (Mr) 267,039. The protein has an obvious domain structure, contains sequence repeats and is structurally related to factor V and ceruloplasmin.
PMID: 6438528 [PubMed - indexed for MEDLINE]
-
Cited by 69 PubMed Central articles
-
The tertiary structure and domain organization of coagulation factor VIII.
Shen BW, Spiegel PC, Chang CH, Huh JW, Lee JS, Kim J, Kim YH, Stoddard BL.
Blood. 2008 Feb 1; 111(3):1240-7. Epub 2007 Oct 26.
[Blood. 2008]
-
Covalent genomic DNA modification patterns revealed by denaturing gradient gel blots.
Laprise SL, Gray MR.
Gene. 2007 Apr 15; 391(1-2):45-52. Epub 2006 Dec 12.
[Gene. 2007]
-
A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels.
Viel KR, Machiah DK, Warren DM, Khachidze M, Buil A, Fernstrom K, Souto JC, Peralta JM, Smith T, Blangero J, et al.
Blood. 2007 May 1; 109(9):3713-24. Epub 2007 Jan 5.
[Blood. 2007]
- » See all...