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Primary structure, gene organization and polypeptide expression of poliovirus RNA.
Kitamura N,
Semler BL,
Rothberg PG,
Larsen GR,
Adler CJ,
Dorner AJ,
Emini EA,
Hanecak R,
Lee JJ,
van der Werf S,
Anderson CW,
Wimmer E.
The primary structure of the poliovirus genome has been determined. The RNA molecule is 7,433 nucleotides long, polyadenylated at the 3' terminus, and covalently linked to a small protein (VPg) at the 5' terminus. An open reading frame of 2,207 consecutive triplets spans over 89% of the nucleotide sequence and codes for the viral polyprotein NCVPOO. Twelve viral polypeptides have been mapped by amino acid sequence analysis and were found to be proteolytic cleavage products of the polyprotein, cleavages occurring predominantly at Gln-Gly pairs.
PMID: 6264310 [PubMed - indexed for MEDLINE]
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Cited by over 100 PubMed Central articles
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The cis-acting replication elements define human enterovirus and rhinovirus species.
Cordey S, Gerlach D, Junier T, Zdobnov EM, Kaiser L, Tapparel C.
RNA. 2008 Aug; 14(8):1568-78. Epub 2008 Jun 9.
[RNA. 2008]
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ReviewEpidemics to eradication: the modern history of poliomyelitis.
De Jesus NH.
Virol J. 2007 Jul 10; 4:70. Epub 2007 Jul 10.
[Virol J. 2007]
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New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features.
Tapparel C, Junier T, Gerlach D, Cordey S, Van Belle S, Perrin L, Zdobnov EM, Kaiser L.
BMC Genomics. 2007 Jul 10; 8:224. Epub 2007 Jul 10.
[BMC Genomics. 2007]
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