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Insertion of the eukaryotic transposable element Ty1 creates a 5-base pair duplication.
The his4-912 mutation results from insertion of a transposable element into the 5'-non-coding region of the his4 gene of yeast. A duplication of 5 base pairs of wild-type his4 DNA flanks the inserted element. The major class of His+ revertants result from excision of most of the transposable element, leaving an inserted segment of 334 base pairs flanked by the 5-base pair repeats.
PMID: 6250062 [PubMed - indexed for MEDLINE]
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Cited by 95 PubMed Central articles
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Ty1 copy number dynamics in Saccharomyces.
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Genetics. 2005 Apr; 169(4):1845-57. Epub 2005 Jan 31.
[Genetics. 2005]
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