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1: Gut. 1969 Aug;10(8):603-8.Click here to read Click here to read Links

Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue.

Gregory RA, Tracy HJ, Agarwal KL, Grossman MI.

Two peptides which are potent stimulants of gastric acid secretion are isolated from Zollinger-Ellison tumour tissue. They have aminoacid constitutions identical with those of human gastrin types I and II as isolated from human antral mucosa, and they are present in similar proportions. Their electrophoretic and chromatographic behaviour corresponds to that of human gastrins. Evidence is presented in respect of the one isolated in greater amount that its aminoacid sequence is probably identical with that of human gastrin type I.

PMID: 5822140 [PubMed - indexed for MEDLINE]

PMCID: PMC1552899