-
Subtype ayw variant of hepatitis B virus. DNA primary structure analysis.
The entire genome of human hepatitis B virus (HBV) occurring in Latvia was sequenced. This sequence, which is 3182 nucleotides long, was compared with the other previously published HBV genomes and was shown to share maximum homology with HBV subtype ayw DNA. The coordinates of 4 main open reading frames as well as hairpin structures are very well conserved in the two genomes. The distribution of nucleotide substitutions among different HBV genomes suggest that the open reading frames P and X can fulfil a coding function. On the basis of primary structure comparison for hepadnaviral DNAs several evolutionary conclusions can be drawn.
PMID: 3996597 [PubMed - indexed for MEDLINE]
-
Cited by 18 PubMed Central articles
-
Reduced hepatitis B virus (HBV)-specific CD4+ T-cell responses in human immunodeficiency virus type 1-HBV-coinfected individuals receiving HBV-active antiretroviral therapy.
Chang JJ, Wightman F, Bartholomeusz A, Ayres A, Kent SJ, Sasadeusz J, Lewin SR.
J Virol. 2005 Mar; 79(5):3038-51.
[J Virol. 2005]
-
Simultaneous detection of multiplex-amplified human immunodeficiency virus type 1 RNA, hepatitis C virus RNA, and hepatitis B virus DNA using a flow cytometer microsphere-based hybridization assay.
Defoort JP, Martin M, Casano B, Prato S, Camilla C, Fert V.
J Clin Microbiol. 2000 Mar; 38(3):1066-71.
[J Clin Microbiol. 2000]
-
Transcription of hepatitis B virus in peripheral blood mononuclear cells from persistently infected patients.
Stoll-Becker S, Repp R, Glebe D, Schaefer S, Kreuder J, Kann M, Lampert F, Gerlich WH.
J Virol. 1997 Jul; 71(7):5399-407.
[J Virol. 1997]
- » See all...