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A form of human basic fibroblast growth factor with an extended amino terminus.
The amino acid sequence of a human placental bFGF was determined by a combination of protein and cDNA sequencing. The placental bFGF consists of 157 amino acid residues with a calculated molecular weight of 17,464 and is highly homologous to bovine pituitary bFGF. The human protein contains an amino terminal extension when compared to the sequence established for bovine bFGF (Esch et al., 1985) and to the sequence of the predicted translation product based on human bFGF cDNA clones (Abraham et al., 1986).
PMID: 3579930 [PubMed - indexed for MEDLINE]
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Cited by 20 PubMed Central articles
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Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis.
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[J Cell Biol. 1998]
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Bikfalvi A, Klein S, Pintucci G, Quarto N, Mignatti P, Rifkin DB.
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[J Cell Biol. 1995]
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Abe T, Okamura K, Ono M, Kohno K, Mori T, Hori S, Kuwano M.
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[J Clin Invest. 1993]
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