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1: FEBS Lett. 1988 Aug 29;236(2):357-61.Click here to read Links

Differential splicing in the 3' non-coding region of rat cytochrome P-452 (P450 IVA1) mRNA.

Earnshaw D, Dale JW, Goldfarb PS, Gibson GG.

Department of Biochemistry, University of Surrey, Guildford, England.

The gene coding for the clofibrate-induced cytochrome P-452 has been isolated from a cDNA library and a full-length cDNA clone sequenced. The sequence was identical with that reported by Hardwick et al. [(1987) J. Biol. Chem. 262, 801-810] apart from the presence of an additional 75 nucleotides inserted adjacent to the 3'-end of the coding region. Northern blot analysis indicates that this is probably a consequence of differential splicing, which may be relevant to the tissue-specific regulation of this gene.

PMID: 3410047 [PubMed - indexed for MEDLINE]