-
Complementary DNA for human T-cell cyclophilin.
Complementary DNA encoding human cyclophilin, a specific cyclosporin A-binding protein, has been isolated from the leukemic T-cell line Jurkat and sequenced. Comparison of the deduced amino acid sequence with the previously determined sequence of bovine thymus cyclophilin reveals only three differences: an additional amino acid at the carboxy terminus end and two internal changes. RNA transfer blot analysis indicates an mRNA size of approximately 1 kb for human T-cell cyclophilin. Phytohaemagglutinin and phorbol myristate acetate induction of T cells treated or not with cyclosporin A affects only marginally the level of cyclophilin mRNA. Southern blot analysis of human genomic DNA digested with different restriction enzymes strongly suggests the existence of a multigene family for cyclophilin.
PMID: 3297675 [PubMed - indexed for MEDLINE]
PMCID: PMC553487
-
Cited by 46 PubMed Central articles
-
Isolation of outer hair cells from the cochlear sensory epithelium in whole-mount preparation using laser capture microdissection.
Anderson CT, Zheng J.
J Neurosci Methods. 2007 May 15; 162(1-2):229-36. Epub 2007 Jan 30.
[J Neurosci Methods. 2007]
-
A Cyanobacterial Gene Encoding Peptidyl-Prolyl cis-trans Isomerase.
Hassidim M, Schwarz R, Lieman-Hurwitz J, Marco E, Ronen-Tarazi M, Kaplan A.
Plant Physiol. 1992 Dec; 100(4):1982-1986.
[Plant Physiol. 1992]
-
The CesA gene family of barley. Quantitative analysis of transcripts reveals two groups of co-expressed genes.
Burton RA, Shirley NJ, King BJ, Harvey AJ, Fincher GB.
Plant Physiol. 2004 Jan; 134(1):224-36. Epub 2003 Dec 30.
[Plant Physiol. 2004]
- » See all...