Molecular cloning of the myelin specific enzyme 2'...[FEBS Lett. 1987]

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1: FEBS Lett. 1987 Jun 29;218(2):261-5. Links

Molecular cloning of the myelin specific enzyme 2',3'-cyclic-nucleotide 3'-phosphohydrolase.

Vogel US, Thompson RJ.

We describe the isolation of cDNA clones for bovine brain 2',3'-cyclic-nucleotide 3'-phosphohydrolase (CNPase, EC 3.1.4.37), the third most abundant protein in central nervous system myelin. The cDNA encodes the complete protein (400 amino acids) and hybridizes to a major size species of mRNA in bovine brain tissue, approx. 2.7 kb in size. CNPase mRNA levels do not appear to be affected in quaking dysmyelinating mutant mice. The sequence reveals probable sites for CNPase phosphorylation by cAMP-dependent protein kinase and a region of homology with haemocyanin.

PMID: 3036592 [PubMed - indexed for MEDLINE]

cDNA cloning and amino acid sequence of bovine brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
J Biol Chem. 1987 Mar 5; 262(7):3256-61.

[J Biol Chem. 1987]
cDNA cloning and amino acid sequence of human brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
Biochem Biophys Res Commun. 1988 Apr 29; 152(2):837-42.

[Biochem Biophys Res Commun. 1988]
Isolation of cDNA clones encoding RICH: a protein induced during goldfish optic nerve regeneration with homology to mammalian 2',3'-cyclic-nucleotide 3'-phosphodiesterases.
Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8621-5.

[Proc Natl Acad Sci U S A. 1995]
Review2',3'-Cyclic-nucleotide 3'-phosphodiesterase. Complementary DNA and gene cloning for mouse enzyme and in situ hybridization of the messenger RNA in mouse brain.
Adv Second Messenger Phosphoprotein Res. 1992; 25:101-10.

[Adv Second Messenger Phosphoprotein Res. 1992]
Review2',3'-cyclic nucleotide 3'-phosphodiesterase, an oligodendrocyte-Schwann cell and myelin-associated enzyme of the nervous system.
Crit Rev Neurobiol. 1989; 4(3):235-301.

[Crit Rev Neurobiol. 1989]
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