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Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene.
Coussens L,
Yang-Feng TL,
Liao YC,
Chen E,
Gray A,
McGrath J,
Seeburg PH,
Libermann TA,
Schlessinger J,
Francke U, et al.
A novel potential cell surface receptor of the tyrosine kinase gene family has been identified and characterized by molecular cloning. Its primary sequence is very similar to that of the human epidermal growth factor receptor and the v-erbB oncogene product; the chromosomal location of the gene for this protein is coincident with the neu oncogene, which suggests that the two genes may be identical.
PMID: 2999974 [PubMed - indexed for MEDLINE]
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Cited by over 100 PubMed Central articles
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Structure-function analysis of nucleolin and ErbB receptors interactions.
Farin K, Di Segni A, Mor A, Pinkas-Kramarski R.
PLoS One. 2009 Jul 3; 4(7):e6128. Epub 2009 Jul 3.
[PLoS One. 2009]
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Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma.
Rosa FE, Silveira SM, Silveira CG, Bérgamo NA, Neto FA, Domingues MA, Soares FA, Caldeira JR, Rogatto SR.
BMC Cancer. 2009 Mar 23; 9:90. Epub 2009 Mar 23.
[BMC Cancer. 2009]
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High prevalence of HER-2/neu overexpression in female breast cancer among an Iraqi population exposed to depleted uranium.
Al-Dujaily EA, Al-Janabi AA, Pierscionek T, Yasseen AA.
J Carcinog. 2008; 7:8.
[J Carcinog. 2008]
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