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Structure of a human common cold virus and functional relationship to other picornaviruses.
Rossmann MG,
Arnold E,
Erickson JW,
Frankenberger EA,
Griffith JP,
Hecht HJ,
Johnson JE,
Kamer G,
Luo M,
Mosser AG, et al.
We report the first atomic resolution structure of an animal virus, human rhinovirus 14. It is strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic regions have been identified. These, and corresponding antigenic sequences of polio and foot-and-mouth disease viruses, reside on external protrusions. A large cleft on each icosahedral face is probably the host cell receptor binding site.
PMID: 2993920 [PubMed - indexed for MEDLINE]
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Cited by over 100 PubMed Central articles
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Ion Channels in Southern Bean Mosaic Virus Capsid.
Silva AM, Cachau RE, Goldstein DJ.
Biophys J. 1987 Oct; 52(4):595-602.
[Biophys J. 1987]
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Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Zhang P, Mueller S, Morais MC, Bator CM, Bowman VD, Hafenstein S, Wimmer E, Rossmann MG.
Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18284-9. Epub 2008 Nov 14.
[Proc Natl Acad Sci U S A. 2008]
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Partitivirus structure reveals a 120-subunit, helix-rich capsid with distinctive surface arches formed by quasisymmetric coat-protein dimers.
Ochoa WF, Havens WM, Sinkovits RS, Nibert ML, Ghabrial SA, Baker TS.
Structure. 2008 May; 16(5):776-86.
[Structure. 2008]
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Structures reported by this article