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1: J Exp Med. 1988 Oct 1;168(4):1247-53.Click here to read Links

Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase.

Department of Immunology, Hospital for Sick Children, Toronto, Canada.

We purified CALLA from human kidney and isolated a cDNA clone reactive with two oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence translated from the CALLA cDNA revealed 100% identity with that of human neutral endopeptidase (NEP, enkephalinase). The distribution of CALLA antigen and NEP in normal tissues are similar.

PMID: 2971756 [PubMed - indexed for MEDLINE]

PMCID: PMC2189092