Complete amino acid sequence of rat liver alcohol ...[Gene. 1986]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Gene. 1986;48(2-3):287-91.Links

Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequence.

Crabb DW, Edenberg HJ.

Alcohol dehydrogenase (ADH) catalyzes the rate-determining reaction in the metabolism of ethanol. We report here the complete nucleotide sequence of a cDNA encoding rat liver ADH, and the deduced amino acid (aa) sequence of the protein. The rat enzyme contains a cluster of aa substitutions and an aa insertion in the region between aa residues 111 and 118, which is near the intron-exon junction reported for the human ADH gene. It also contains an additional cysteine in the highly variable region from aa residues 108-125 which may account for the unusual lability of rat ADH compared with ADH from other species.

PMID: 2881847 [PubMed - indexed for MEDLINE]

Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase.
Proc Natl Acad Sci U S A. 1985 Apr; 82(8):2262-6.

[Proc Natl Acad Sci U S A. 1985]
Molecular cloning of mouse alcohol dehydrogenase-B2 cDNA: nucleotide sequences of the class III ADH genes evolve slowly even for silent substitutions.
DNA Seq. 1992; 3(3):167-75.

[DNA Seq. 1992]
Cloning and sequencing of cDNA encoding baboon liver alcohol dehydrogenase: evidence for a common ancestral lineage with the human alcohol dehydrogenase beta subunit and for class I ADH gene duplications predating primate radiation.
Proc Natl Acad Sci U S A. 1989 Jul; 86(14):5454-8.

[Proc Natl Acad Sci U S A. 1989]
Genomic structure and expression of the ADH7 gene encoding human class IV alcohol dehydrogenase, the form most efficient for retinol metabolism in vitro.
J Biol Chem. 1995 Mar 3; 270(9):4305-11.

[J Biol Chem. 1995]
ReviewMolecular genetics and evolution of baboon liver alcohol dehydrogenase.
Alcohol Alcohol Suppl. 1991; 1:85-90.

[Alcohol Alcohol Suppl. 1991]
» See reviews... | » See all...

Cited by 3 PubMed Central articles

Amino acid substitution at the Adh locus of Drosophila is facilitated by small population size.
Ohta T. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4548-51.

[Proc Natl Acad Sci U S A. 1993]
Regulation of gene expression of class I alcohol dehydrogenase by glucocorticoids.
Dong Y, Poellinger L, Okret S, Höög JO, von Bahr-Lindström H, Jörnvall H, Gustafsson JA. Proc Natl Acad Sci U S A. 1988 Feb; 85(3):767-71.

[Proc Natl Acad Sci U S A. 1988]
Cloning and sequencing of cDNA encoding baboon liver alcohol dehydrogenase: evidence for a common ancestral lineage with the human alcohol dehydrogenase beta subunit and for class I ADH gene duplications predating primate radiation.
Trezise AE, Godfrey EA, Holmes RS, Beacham IR. Proc Natl Acad Sci U S A. 1989 Jul; 86(14):5454-8.

[Proc Natl Acad Sci U S A. 1989]

Recent Activity

Clear Turn Off Turn On

Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequ...Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequence.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequence.

Related articles

Cited by 3 PubMed Central articles

Recent Activity