Sequence analysis of the NgoPII methyltransferase ...[Nucleic Acids Res. 1988]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Nucleic Acids Res. 1988 May 25;16(10):4369-87. Links

Sequence analysis of the NgoPII methyltransferase gene from Neisseria gonorrhoeae P9: homologies with other enzymes recognizing the sequence 5'-GGCC-3'.

Sullivan KM, Saunders JR.

Department of Microbiology, University of Liverpool, UK.

Recombinant plasmids harbouring the functional M.NgoPII methyltransferase (specificity 5'-GGCC-3') were isolated from amplified gene libraries of gonococcal chromosomal DNA cloned in pBR322 and in Escherichia coli RR1. The M.NgoPII gene was localized by sub-cloning and the nucleotide sequence of a cloned 1.6 kb segment of Neisseria gonorrhoeae DNA harbouring the methylase gene was determined. This data, coupled with sub-cloning experiments and in vitro transcription-translation studies, indicates a theoretical size of 38.5 kd for the methylase protein. The predicted amino acid sequence of the methylase contains significant regions of homology with the projected sequences of other cytosine-modifying methylases, upon which the activity of these enzymes is likely to depend.

PMID: 2837733 [PubMed - indexed for MEDLINE]

PMCID: PMC336636

Nucleotide sequence and genetic organization of the NgoPII restriction-modification system of Neisseria gonorrhoeae.
Mol Gen Genet. 1989 Apr; 216(2-3):380-7.

[Mol Gen Genet. 1989]
Nucleotide sequence of the BsuRI restriction-modification system.
Nucleic Acids Res. 1985 Sep 25; 13(18):6403-21.

[Nucleic Acids Res. 1985]
Characterization of the archaeal, plasmid-encoded type II restriction-modification system MthTI from Methanobacterium thermoformicicum THF: homology to the bacterial NgoPII system from Neisseria gonorrhoeae.
J Bacteriol. 1992 Sep; 174(17):5719-26.

[J Bacteriol. 1992]
ReviewResistance to alkylation damage in Escherichia coli: role of the Ada protein in induction of the adaptive response.
Mutat Res. 1990 Nov-Dec; 233(1-2):53-72.

[Mutat Res. 1990]
ReviewDNA restriction and modification systems in Neisseria gonorrhoeae.
Clin Microbiol Rev. 1989 Apr; 2 Suppl:S78-82.

[Clin Microbiol Rev. 1989]
» See reviews... | » See all...

Cited by 20 PubMed Central articles

The cyanobacterium Synechocystis sp. strain PCC 6803 expresses a DNA methyltransferase specific for the recognition sequence of the restriction endonuclease PvuI.
Scharnagl M, Richter S, Hagemann M. J Bacteriol. 1998 Aug; 180(16):4116-22.

[J Bacteriol. 1998]
Effect of site-specific methylation on restriction endonucleases and DNA modification methyltransferases.
Nelson M, Raschke E, McClelland M. Nucleic Acids Res. 1993 Jul 1; 21(13):3139-54.

[Nucleic Acids Res. 1993]
Locations of genetic markers on the physical map of the chromosome of Neisseria gonorrhoeae FA1090.
Dempsey JA, Cannon JG. J Bacteriol. 1994 Apr; 176(7):2055-60.

[J Bacteriol. 1994]
» See all...

Recent Activity

Clear Turn Off Turn On

Sequence analysis of the NgoPII methyltransferase gene from Neisseria gonorrhoeae P9: homo...Sequence analysis of the NgoPII methyltransferase gene from Neisseria gonorrhoeae P9: homologies with other enzymes recognizing the sequence 5'-GGCC-3'.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Sequence analysis of the NgoPII methyltransferase gene from Neisseria gonorrhoeae P9: homologies with other enzymes recognizing the sequence 5'-GGCC-3'.

Related articles

Cited by 20 PubMed Central articles

Recent Activity