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1: Mol Endocrinol. 1989 Oct;3(10):1585-8.Click here to read Links

Cloning and sequencing of the bovine gastrin gene.

Lund T, Olsen J, Rehfeld JF.

University Department of Clinical Chemistry, Rigshospitalet, Copenhagen, Denmark.

In order to deduce the primary structure of bovine preprogastrin we therefore sequenced a gastrin DNA clone isolated from a bovine liver cosmid library. Bovine preprogastrin comprises 104 amino acids and consists of a signal peptide, a 37 amino acid spacer-sequence, the gastrin-34 sequence followed by an amidation-site (Gly-Arg-Arg), and a C-terminal nonapeptide. Comparison with human, porcine, and rat cDNA sequences revealed extensive homology in the coding region as well as in short noncoding structures.

PMID: 2608050 [PubMed - indexed for MEDLINE]