The human cytochrome P450 CYP3 locus: assignment t...[Hum Genet. 1989]

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1: Hum Genet. 1989 Jan;81(2):171-4.Links

The human cytochrome P450 CYP3 locus: assignment to chromosome 7q22-qter.

Spurr NK, Gough AC, Stevenson K, Wolf CR.

Human Genetic Resources, Imperial Cancer Research Fund, Clare Hall Laboratories, Herts, UK.

The cytochrome P-450s are a large multigene family of enzymes involved in the metabolism and detoxification of drugs and chemicals. Using a full length cDNA clone for the human nifedipine oxidase gene (CYP3) and a panel of human-rodent somatic cell hybrids, we have assigned this gene family to chromosome 7q22-qter. A search for RFLPs using this probe yielded no results.

PMID: 2563251 [PubMed - indexed for MEDLINE]

Assignment of the human cytochrome P-450 nifedipine oxidase gene (CYP3A4) to chromosome 7 at band q22.1 by fluorescence in situ hybridization.
Jpn J Hum Genet. 1992 Jun; 37(2):133-8.

[Jpn J Hum Genet. 1992]
A cytochrome P-450 gene family mapped to human chromosome 19.
Ann Hum Genet. 1985 Oct; 49(Pt 4):267-74.

[Ann Hum Genet. 1985]
The gene CYP3 encoding P450pcn1 (nifedipine oxidase) is tightly linked to the gene COL1A2 encoding collagen type 1 alpha on 7q21-q22.1.
Am J Hum Genet. 1988 Sep; 43(3):280-4.

[Am J Hum Genet. 1988]
ReviewEvolution of the P450 gene superfamily and regulation of the murine Cyp1a1 gene.
Biochem Soc Trans. 1990 Feb; 18(1):7-10.

[Biochem Soc Trans. 1990]
ReviewThe cytochrome P450 gene superfamily.
Int J Exp Pathol. 1991 Jun; 72(3):349-63.

[Int J Exp Pathol. 1991]
» See reviews... | » See all...

Cited by 1 PubMed Central article

Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity.
Miles JS, Bickmore W, Brook JD, McLaren AW, Meehan R, Wolf CR. Nucleic Acids Res. 1989 Apr 25; 17(8):2907-17.

[Nucleic Acids Res. 1989]

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