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The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution.
Laboratory of Molecular Biophysics, Oxford, UK.
The structure of foot-and-mouth disease virus has been determined at close to atomic resolution by X-ray diffraction without experimental phase information. The virus shows similarities with other picornaviruses but also several unique features. The canyon or pit found in other picornaviruses is absent; this has important implications for cell attachment. The most immunogenic portion of the capsid, which acts as a potent peptide vaccine, forms a disordered protrusion on the virus surface.
PMID: 2537470 [PubMed - indexed for MEDLINE]
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Structures reported by this article