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Primary structure of a human protein kinase regulator protein.
Max Planck Institut für Immunbiologie, Freiburg, F.R.G.
A human T-cell cDNA is characterized which codes for a protein closely related to a family of proteins alternatively described as co-regulators, of monoamine biosynthesis in neurons and as inhibitors of protein kinase C. The predicted human protein is 28 kDa and has a pI of 4.5. Alignment of putative protein sequences shows strong conservation from Drosophila to man. Several mRNA transcripts hybridizing to the cDNA are seen in human epithelial and T-cell lines and in various mouse tissues.
PMID: 2015305 [PubMed - indexed for MEDLINE]
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Cited by 8 PubMed Central articles