The Calyptogena magnifica chemoautotrophic symbiont genome.
Newton IL,
Woyke T,
Auchtung TA,
Dilly GF,
Dutton RJ,
Fisher MC,
Fontanez KM,
Lau E,
Stewart FJ,
Richardson PM,
Barry KW,
Saunders E,
Detter JC,
Wu D,
Eisen JA,
Cavanaugh CM.
Harvard University, 16 Divinity Avenue, Biolabs 4080, Cambridge, MA 02138, USA.
Chemoautotrophic endosymbionts are the metabolic cornerstone of hydrothermal vent communities, providing invertebrate hosts with nearly all of their nutrition. The Calyptogena magnifica (Bivalvia: Vesicomyidae) symbiont, Candidatus Ruthia magnifica, is the first intracellular sulfur-oxidizing endosymbiont to have its genome sequenced, revealing a suite of metabolic capabilities. The genome encodes major chemoautotrophic pathways as well as pathways for biosynthesis of vitamins, cofactors, and all 20 amino acids required by the clam.
PMID: 17303757 [PubMed - indexed for MEDLINE]