Molecular cloning of human epidermal transglutamin...[Biochem Biophys Res Commun. 1991]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Biochem Biophys Res Commun. 1991 Mar 29;175(3):906-13. Links

Molecular cloning of human epidermal transglutaminase cDNA from keratinocytes in culture.

Yamanishi K, Liew FM, Konishi K, Yasuno H, Doi H, Hirano J, Fukushima S.

Department of Dermatology, Kyoto Prefectural University of Medicine, Japan.

We have isolated a cDNA encoding human epidermal transglutaminase, a key enzyme of terminal differentiation of keratinocytes. A cDNA library from cultured human keratinocytes was screened by a PCR-amplified partial cDNA fragment of the enzyme with oligonucleotide primers based on the homology of the transglutaminase family. The cDNA is 2734 bp coding a protein of 817 amino acids. The several regions including the active site cysteine residue are highly conserved among the transglutaminase family. However, the charged N-terminal domain is unique to the epidermal transglutaminse, suggesting that the region is involved in the function of the enzyme in keratinocytes.

PMID: 1673840 [PubMed - indexed for MEDLINE]

Isolation of cDNA for human epidermal type I transglutaminase.
J Invest Dermatol. 1991 Feb; 96(2):285-8.

[J Invest Dermatol. 1991]
Isolation of a cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription-polymerase chain reaction with degenerate primers.
J Biol Chem. 1998 Feb 6; 273(6):3452-60.

[J Biol Chem. 1998]
The complete amino acid sequence of the human transglutaminase K enzyme deduced from the nucleic acid sequences of cDNA clones.
J Biol Chem. 1991 Jan 5; 266(1):536-9.

[J Biol Chem. 1991]
Primary structure of keratinocyte transglutaminase.
Proc Natl Acad Sci U S A. 1990 Dec; 87(23):9333-7.

[Proc Natl Acad Sci U S A. 1990]
ReviewKeratinocyte transglutaminase: differentiation marker and member of an extended family.
Epithelial Cell Biol. 1992 Jul; 1(3):128-37.

[Epithelial Cell Biol. 1992]
» See reviews... | » See all...

Cited by 4 PubMed Central articles

Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C.
Ohba M, Ishino K, Kashiwagi M, Kawabe S, Chida K, Huh NH, Kuroki T. Mol Cell Biol. 1998 Sep; 18(9):5199-207.

[Mol Cell Biol. 1998]
Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase).
Matsuki M, Yamashita F, Ishida-Yamamoto A, Yamada K, Kinoshita C, Fushiki S, Ueda E, Morishima Y, Tabata K, Yasuno H, et al. Proc Natl Acad Sci U S A. 1998 Feb 3; 95(3):1044-9.

[Proc Natl Acad Sci U S A. 1998]
Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme.
Geng YJ, Libby P. Am J Pathol. 1995 Aug; 147(2):251-66.

[Am J Pathol. 1995]
» See all...

Recent Activity

Clear Turn Off Turn On

Molecular cloning of human epidermal transglutaminase cDNA from keratinocytes in culture.Molecular cloning of human epidermal transglutaminase cDNA from keratinocytes in culture.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Molecular cloning of human epidermal transglutaminase cDNA from keratinocytes in culture.

Related articles

Cited by 4 PubMed Central articles

Recent Activity