Structure and control of phosphofructokinase from ...[Nature. 1979]

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1: Nature. 1979 Jun 7;279(5713):500-4.Links

Structure and control of phosphofructokinase from Bacillus stearothermophilus.

Evans PR, Hudson PJ.

The allosteric enzyme phosphofructokinase binds its substrate fructose-6-phosphate between two subunits of the tetramer, and allosteric effectors between another pair of subunits. The effector binding site accommodates both the activator and the inhibitor. The substrate cooperativity and allosteric control are mediated by these ligand bridges between subunits.

PMID: 156307 [PubMed - indexed for MEDLINE]

Phosphofructokinase: structure and control.
Philos Trans R Soc Lond B Biol Sci. 1981 Jun 26; 293(1063):53-62.

[Philos Trans R Soc Lond B Biol Sci. 1981]
Structural basis of the allosteric behaviour of phosphofructokinase.
Nature. 1990 Jan 11; 343(6254):140-5.

[Nature. 1990]
Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products.
J Mol Biol. 1988 Dec 20; 204(4):973-94.

[J Mol Biol. 1988]
ReviewRegulatory properties and the development of structure in phosphofructokinase.
Arch Biol Med Exp (Santiago). 1987; 20(3-4):359-70.

[Arch Biol Med Exp (Santiago). 1987]
ReviewPhosphofructokinase: structure and function.
Curr Top Cell Regul. 1979; 15:109-41.

[Curr Top Cell Regul. 1979]
» See reviews... | » See all...

Cited by 25 PubMed Central articles

Glycolysis and the regulation of glucose transport in Lactococcus lactis spp. lactis in batch and fed-batch culture.
Papagianni M, Avramidis N, Filiousis G. Microb Cell Fact. 2007 May 24; 6:16. Epub 2007 May 24.

[Microb Cell Fact. 2007]
Effects of protein-ligand associations on the subunit interactions of phosphofructokinase from B. stearothermophilus.
Quinlan RJ, Reinhart GD. Biochemistry. 2006 Sep 26; 45(38):11333-41.

[Biochemistry. 2006]
A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity.
Mosher RA, Durrant WE, Wang D, Song J, Dong X. Plant Cell. 2006 Jul; 18(7):1750-65. Epub 2006 Jun 9.

[Plant Cell. 2006]
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Structures reported by this article

Phosphofructokinase. Structure And Control

PDB: 4PFK

Source: Geobacillus stearothermophilus

Method: X-Ray Diffraction | Resolution: 2.4 Å
» See all 3 structures...

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Structures reported by this article

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