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1: Science. 2003 Oct 3;302(5642):100-3.Click here to read Links
Comment in:
Trends Plant Sci. 2006 Nov;11(11):524-5; author reply 526-8.

Identification of a plant nitric oxide synthase gene involved in hormonal signaling.

Guo FQ, Okamoto M, Crawford NM.

Section of Cell and Developmental Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA.

Nitric oxide (NO) serves as a signal in plants. An Arabidopsis mutant (Atnos1) was identified that had impaired NO production, organ growth, and abscisic acid-induced stomatal movements. Expression of AtNOS1 with a viral promoter in Atnos1 mutant plants resulted in overproduction of NO. Purified AtNOS1 protein used the substrates arginine and nicotinamide adenine dinucleotide phosphate and was activated by Ca2+ and calmodulin-like mammalian endothelial nitric oxide synthase and neuronal nitric oxide synthase, yet it is a distinct enzyme with no sequence similarities to any mammalian isoform. Thus, AtNOS1 encodes a distinct nitric oxide synthase that regulates growth and hormonal signaling in plants.

PMID: 14526079 [PubMed - indexed for MEDLINE]