Molecular cloning and binding properties of the hu...[Biochem Biophys Res Commun. 1992]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Biochem Biophys Res Commun. 1992 Apr 15;184(1):310-6. Links

Molecular cloning and binding properties of the human type II activin receptor.

Donaldson CJ, Mathews LS, Vale WW.

Clayton Foundation Laboratories for Peptide Biology, Salk Institute, La Jolla, CA 92037.

A full-length cDNA for the type II human activin receptor was cloned by hybridization from a human testis cDNA library. The sequence encodes a 513 amino acid protein that is 99% identical, at the amino acid level, with the mouse type II activin receptor. The type II human activin receptor consists of an extracellular domain that specifically binds activin A with a Kd of 360 pM, a single-membrane spanning domain, and an intracellular kinase domain with predicted serine/threonine specificity.

PMID: 1314589 [PubMed - indexed for MEDLINE]

Expression cloning of an activin receptor, a predicted transmembrane serine kinase.
Cell. 1991 Jun 14; 65(6):973-82.

[Cell. 1991]
Cloning and sequencing of a rat type II activin receptor.
FEBS Lett. 1992 Nov 2; 312(1):53-6.

[FEBS Lett. 1992]
Molecular characterization of a type I serine-threonine kinase receptor for TGF-beta and activin in the rat pituitary tumor cell line GH3.
Exp Cell Res. 1995 Jan; 216(1):208-14.

[Exp Cell Res. 1995]
ReviewThree-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase.
Nat Struct Biol. 1999 Jan; 6(1):18-22.

[Nat Struct Biol. 1999]
ReviewExpression cloning of TGF-beta receptors.
Mol Reprod Dev. 1992 Jun; 32(2):105-10.

[Mol Reprod Dev. 1992]
» See reviews... | » See all...

Cited by 3 PubMed Central articles

Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Angstrom resolution.
Han S, Loulakis P, Griffor M, Xie Z. Protein Sci. 2007 Oct; 16(10):2272-7.

[Protein Sci. 2007]
A chimeric serine/threonine kinase receptor system reveals the potential of multiple type II receptors to cooperate with transforming growth factor-beta type I receptor.
Muramatsu M, Yan J, Eto K, Tomoda T, Yamada R, Arai K. Mol Biol Cell. 1997 Mar; 8(3):469-80.

[Mol Biol Cell. 1997]
New nucleotide sequence data on the EMBL File Server.
. Nucleic Acids Res. 1992 Jul 25; 20(14):3797-812.

[Nucleic Acids Res. 1992]

Recent Activity

Clear Turn Off Turn On

Molecular cloning and binding properties of the human type II activin receptor.Molecular cloning and binding properties of the human type II activin receptor.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Molecular cloning and binding properties of the human type II activin receptor.

Related articles

Cited by 3 PubMed Central articles

Recent Activity