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1: Antimicrob Agents Chemother. 2003 Apr;47(4):1407-9.Click here to read Click here to read Links

In vitro metronidazole and tinidazole activities against metronidazole-resistant strains of Trichomonas vaginalis.

Crowell AL, Sanders-Lewis KA, Secor WE.

Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30341, USA.

The in vitro activities of tinidazole and metronidazole against Trichomonas vaginalis isolates clinically resistant to metronidazole were compared. Minimal lethal concentrations (MLCs) of tinidazole were significantly lower than MLCs of metronidazole. Increased metronidazole resistance correlated with increased tinidazole resistance. These data support a role for tinidazole in the treatment of trichomoniasis.

PMID: 12654679 [PubMed - indexed for MEDLINE]

PMCID: PMC152533

Patient Drug Information

  • Tinidazole (Tindamax® )

    Tinidazole is used to treat trichomoniasis (a sexually transmitted disease that can affect men and women), giardiasis (an infection of the intestine that can cause diarrhea, gas, and stomach cramps), and amebiasis (an in...

  • Source: AHFS Consumer Medication Information