Bsp1p/Ypr171p is an adapter that directly links so...[FEBS Lett. 2003]

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1: FEBS Lett. 2003 Feb 27;537(1-3):35-41. Links

Bsp1p/Ypr171p is an adapter that directly links some synaptojanin family members to the cortical actin cytoskeleton in yeast.

Wicky S, Frischmuth S, Singer-Krüger B.

Institute for Biochemistry, University of Stuttgart, Pfaffenwaldring 55, Germany.

In this study we identified a novel protein, Bsp1p, that interacts directly with two yeast synaptojanins, Sjl2p and Sjl3p, but not with Sjl1p. The interaction takes place via the Sac1/polyphosphoinositide phosphatase domain, whose conserved C-terminal region is important for binding. Subcellular localization and genetic interactions revealed a function of Bsp1p in the cortical actin cytoskeleton. A fraction of Bsp1p was found to be membrane-associated. Studies with mutants of phosphatidylinositol 4-kinase, PIK1, suggested that the interaction with membranes is facilitated by phosphoinositides. We propose that Bsp1p is an adapter that links Sjl2p and Sjl3p to the cortical actin cytoskeleton.

PMID: 12606027 [PubMed - indexed for MEDLINE]

SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.
J Cell Biol. 1993 Jul; 122(1):79-94.

[J Cell Biol. 1993]
The Saccharomyces cerevisiae actin cytoskeletal component Bsp1p has an auxiliary role in actomyosin ring function and in the maintenance of bud-neck structure.
Genetics. 2008 Apr; 178(4):1903-14.

[Genetics. 2008]
Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.
Mol Biol Cell. 2001 Aug; 12(8):2396-411.

[Mol Biol Cell. 2001]
ReviewSac phosphatase domain proteins.
Biochem J. 2000 Sep 1; 350 Pt 2:337-52.

[Biochem J. 2000]
ReviewSynthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.
Biochim Biophys Acta. 2007 Mar; 1771(3):353-404. Epub 2007 Feb 6.

[Biochim Biophys Acta. 2007]
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Cited by 7 PubMed Central articles

Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast.
Narayanaswamy R, Moradi EK, Niu W, Hart GT, Davis M, McGary KL, Ellington AD, Marcotte EM. J Proteome Res. 2009 Jan; 8(1):6-19.

[J Proteome Res. 2009]
The Saccharomyces cerevisiae actin cytoskeletal component Bsp1p has an auxiliary role in actomyosin ring function and in the maintenance of bud-neck structure.
Wright DJ, Munro E, Corbett M, Bentley AJ, Fullwood NJ, Murray S, Price C. Genetics. 2008 Apr; 178(4):1903-14.

[Genetics. 2008]
ReviewSynthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.
Strahl T, Thorner J. Biochim Biophys Acta. 2007 Mar; 1771(3):353-404. Epub 2007 Feb 6.

[Biochim Biophys Acta. 2007]
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