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Genome structure of Ebola virus subtype Reston: differences among Ebola subtypes. Brief report.
Department of Virology 1, National Institute of Infectious Diseases, Tokyo, Japan.
We determined the complete genome sequence of Ebola virus subtype Reston (EBO-R) in the Philippines in 1996. The deduced transcriptional signals were highly conserved among Ebola viruses except for the stop signal of L genes. The intergenic regions were composed of 4 to 7 nucleotides, and of 2 characteristic overlaps and a long intergenic region. The glycoprotein (GP) had several amino acid differences from EBO-R isolated in 1989 and 1992. The variety of GP sequences strongly suggests the independent introduction of EBO-R from unknown natural reservoirs in 1996.
PMID: 11722021 [PubMed - indexed for MEDLINE]
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Cited by 2 PubMed Central articles
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Antigen capture enzyme-linked immunosorbent assay for specific detection of Reston Ebola virus nucleoprotein.
Ikegami T, Niikura M, Saijo M, Miranda ME, Calaor AB, Hernandez M, Acosta LP, Manalo DL, Kurane I, Yoshikawa Y, et al.
Clin Diagn Lab Immunol. 2003 Jul; 10(4):552-7.
[Clin Diagn Lab Immunol. 2003]
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Analysis of linear B-cell epitopes of the nucleoprotein of ebola virus that distinguish ebola virus subtypes.
Niikura M, Ikegami T, Saijo M, Kurata T, Kurane I, Morikawa S.
Clin Diagn Lab Immunol. 2003 Jan; 10(1):83-7.
[Clin Diagn Lab Immunol. 2003]